3M™ Promogran Prisma™ Matrix

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Composed of balanced combination of collagen, oxidized regenerated cellulose (ORC), and silver ORC

Maintain moist environment

Antimicrobial protection

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  • Composed of balanced combination of collagen, oxidized regenerated cellulose (ORC), and silver ORC
  • Maintain moist environment
  • Antimicrobial protection

3M™ Promogran Prisma™ Matrix is comprised of a sterile, freeze dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver-ORC. Silver-ORC contains 25% w/w ionically bound silver, a well-known antimicrobial agent.

Collagen is essential for new tissue generation. This family of structural proteins attracts cells to the wound area and forms the underlying layer for cell adhesion that induces cell growth and helps build new proteins. In a wound dressing, the benefits of collagen may be further enhanced with the addition of the right balance of components, namely, oxidized regenerated cellulose (ORC) and often, silver for its antimicrobial properties. The dressings maintain a moist microenvironment that is conducive to granulation tissue formation, epithelialization, and rapid wound healing. The matrix is a freeze dried composite that consists of 55% collagen and 45% oxidized regenerated cellulose (ORC) and additionally contains 1% of silver-ORC. The silver, a well-known antimicrobial agent, provides antimicrobial protection against bacteria in wounds at risk of infection.


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¹ ² Simmons R., et al. Effect of collagen ORC silver on bacterial proteases. Poster presented at: SAWC; May 1 – 5, 2013; Denver, CO US. ² The Power of Balance in Wound Care. KCI Comparative Effectiveness of Promogran Prisma™ Matrix vs Endoform™ Dermal Template. April 2018.